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  • Senolytic Balm

    Senolytic Balm

    1.7 oz | 50 g

    A rich, lipid-based treatment that delivers intensive nourishment to support cellular longevity, skin structure, and barrier health for resilient, plump, luminous skin.


    DETAILS

    Senolytic Balm melts into skin with a rich, lipid-dense texture that envelops dry, mature, and aging skin in immediate comfort, leaving it deeply replenished, plump, and luminous. Applied as the final step in your skincare regimen, its' nutrient-rich formula delivers intensive nourishment while sealing in preceding steps. By reinforcing the skin barrier and reducing transepidermal water loss, it helps retain essential moisture and preserve the efficacy of your regimen. Rich and restorative on the surface, the balm delivers sophisticated age-delay science underneath.

    The formula takes a senotherapeutic approach to cellular senescence, a hallmark of aging, with the senoyltic ingredient Fisetin. Senescent cells are aging or stressed cells that have stopped dividing but remain active, releasing signals that can contribute to inflammation and visible signs of aging. 

    Antioxidants help support collagen synthesis and defend against oxidative stress. Barrier-supportive lipids further replenish dry, depleted skin and support lasting moisture. With continued use, skin feels deeply nourished, resilient, and luminous.

    Fisetin, a Senolytic 
    A naturally occurring flavonoid found in fruits and vegetables, fisetin acts as a senolytic compound, helping to support cellular longevity by reducing the accumulation of aged, stressed cells. Fisetin helps protect against oxidative stress, support healthy cellular turnover, and maintain resilience.

    Resveratrol
    A powerful polyphenol derived from Japanese knotweed, resveratrol is a potent antioxidant that protects skin from environmental stressors and free radical damage. It helps soothe inflammation, support collagen production, and improve skin elasticity.

    Coenzyme Q10
    CoQ10 is a naturally occurring antioxidant in the body that helps energize skin cells and neutralize oxidative damage caused by environmental stress. In topical formulations, CoQ10 supports cellular repair and reduces the visible signs of aging.

    Tetrahexyldecyl Ascorbate 
    A stable, oil-soluble form of vitamin C that penetrates deeply into the skin, this vitamin C ester provides powerful antioxidant protection while supporting collagen synthesis. It helps brighten skin tone, reduce hyperpigmentation, and defend against oxidative stress.

    Simmondsia Chinensis (Jojoba) Seed Oil, Butyrospermum Parkii (Shea) Butter, Camellia Oleifera Seed Oil, Caprylic/Capric Triglyceride, Euphorbia Cerifera (Candelilla) Wax, Sorbitan Olivate, Squalane, Coco-Caprylate/Caprate, Tetrahexyldecyl Ascorbate, Helianthus Annuus (Sunflower) Seed Oil, Resveratrol, Fisetin, Mixed Tocopherol, Ubiquinone, Ethyl Ferulate, Humulus Lupulus (Hop) Extract, Alkanna Tinctoria Root Extract

    1. Where does Senolytic Balm fit into my regimen?
    Senolytic Balm is designed to be the final treatment step in your routine. When using a complete regimen, apply it after Emulsion. It can also be applied directly over Serum(s) or Oil as your final step.

    Recommended order of application:
    Rinse with water or Cleanse → Tonic/Mist → Serum(s) → Oil → Emulsion → Balm → Sunscreen (AM)

    2. Can Senolytic Balm be used in the morning?
    Yes. Senolytic Balm can be used morning and night. In the morning, apply it as your final treatment step before sunscreen. In the evening, it is especially beneficial as the final step to help seal in preceding products and reduce overnight transepidermal water loss (TEWL), supporting lasting hydration and barrier function.

    3. Does Senolytic Balm replace other actives in my regimen, such as retinol or an emulsion?
    No. Senolytic Balm is designed to complement, rather than replace, other Marie Veronique products. It can be used alongside retinoids, antioxidants, and emulsions, with no contraindications within a Marie Veronique regimen.

    By supporting a healthier cellular environment, Senolytic Balm helps promote skin responsiveness and complements the role of other age-delay actives in your regimen. Like all of our formulas, it can be used daily or incorporated throughout the week according to what works best for your skin and routine.

    Key benefits

    ADDRESSES CELLULAR SENESCENCE

    Takes a senotherapeutic approach to cellular senescence, a hallmark of aging, to help support healthier cell function and longevity.

    SUPPORTS SKIN STRUCTURE

    Supports fibroblast function and collagen synthesis to help maintain the extracellular matrix—the structural network that contributes to skin firmness and resilience.

    DEFENDS AGAINST OXIDATIVE STRESS

    Provides antioxidant protection against free radicals and environmental stressors that cause oxidative stress—cellular damage that can accelerate visible signs of aging.

    STRENGTHENS BARRIER FUNCTION

    Replenishes essential lipids to reinforce the skin barrier and reduce transepidermal water loss (TEWL), helping skin retain moisture and stay resilient.

    REPLENISHES DRY, DEPLETED SKIN

    Delivers intensive lipid nourishment to dry, mature, and depleted skin, leaving it feeling deeply moisturized, plump, supple, and luminous.

    How to use

    As the final step in your evening regimen, apply a generous, pea-sized amount to your face, neck, and chest after serums, oil, and emulsion. Gently massage any excess product around the eye contour, avoiding direct contact with the lash line or lid. Ideal for normal to dry or mature skin.


    Dosage

    Generous, pea-sized amount


    Regimen integration

    Final PM step, after serums, oil & emulsions


    Optimal pairings

    Multi-Retinol Night Emulsion

    Balm vs Serum

    Senolytic Serum and Senolytic Balm are designed to complement one another. The lightweight Serum provides a more targeted approach to supporting cellular longevity, while the Balm builds on that approach with lipid nourishment, antioxidant protection, and barrier support.

    Senolytic Balm
    Senolytic Serum
    Primary Role
    Senolytic Balm Cellular longevity + collagen and barrier support
    Senolytic Serum Targeted cellular longevity support
    Key Actives
    Senolytic Balm Fisetin, Resveratrol, CoQ10 + Tetrahexyldecyl Ascorbate (THD)
    Senolytic Serum Encapsulated Fisetin, Astragalus + Magnesium Ascorbyl Phosphate (MAP)
    Texture
    Senolytic Balm Rich, nourishing lipid-based balm
    Senolytic Serum Lightweight, layerable serum
    Best For
    Senolytic Balm Normal-to-dry, mature, sensitive, or depleted skin
    Senolytic Serum All skin types seeking targeted cellular longevity support
    When to Use
    Senolytic Balm PM, as the final step in your regimen
    Senolytic Serum PM, after cleansing and toning

    Why use both?

    The formulas are designed to play different roles. Senolytic Serum provides targeted cellular longevity support, while Senolytic Balm broadens that approach with antioxidant protection, collagen support, and intensive barrier nourishment. Layer together for a more comprehensive approach to visible aging.