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  • Senolytic Serum

    Senolytic Serum

    1 fl oz | 30 mL

    A lightweight, targeted skin-longevity serum powered by encapsulated fisetin to support healthy cellular function and address age-related changes associated with cellular senescence. Designed to promote skin resilience and recovery for smoother, firmer, more even-looking skin over time.


    Please note this item will ship 10/13. Orders with additional items will ship separately.

    DETAILS

    Senolytic Serum is a targeted skin-longevity treatment developed to address cellular senescence, a hallmark of aging. Senescent cells are aging or stressed cells that have stopped dividing but remain active, releasing signals that can contribute to inflammation and visible signs of aging.

    At the center of the formula is fisetin, a naturally occurring flavonoid extensively investigated in longevity research for its potential senolytic activity. To help preserve its integrity within an aqueous topical system, fisetin is delivered in an encapsulated form designed to protect it from degradation and support its stability.

    Encapsulated fisetin is combined with astragalus root and Magnesium Ascorbyl Phosphate (MAP), a stable vitamin C derivative, to provide antioxidant support and help maintain healthy fibroblast function, promote collagen synthesis, and extracellular matrix integrity.

    By supporting a healthier cellular environment, Senolytic Serum helps improve skin resilience and recovery capacity while complementing retinoids, antioxidants, peptides, and other age-delay treatments. Over time, skin appears smoother, firmer, more even-toned, and better able to respond to environmental and age-related stress.

    Encapsulated Fisetin, a Senolytic
    A naturally occurring flavonoid that has been extensively investigated in longevity research for its potential senolytic activity. In this formula, fisetin is encapsulated to protect it from degradation and support its stability within the aqueous topical system.

    Astragalus Root
    A botanical containing astragalosides and other bioactive compounds. Included for its antioxidant and skin-supportive properties and its potential to support healthy fibroblast and extracellular matrix function.

    Magnesium Ascorbyl Phosphate (MAP)
    A stable, water-soluble vitamin C derivative that provides antioxidant support and supports collagen synthesis and overall skin resilience.

    Water/Aqua/Eau, Vinegar, Hydroxypropyl Starch Phosphate, Dipropylene Glycol, Glyceryl Caprylate, Tocopherol Polysarcosine, Magnesium Ascorbyl Phosphate, Maltodextrin, Fisetin, Xanthophylls, Chitosan, Sodium Palmitoyl Proline, Glycerin, Propanediol, Nymphaea Alba Flower Extract, Caprylhydroxamic Acid, Phosphatidylcholine, Astragalus Membranaceus Root Powder, Lecithin, Tocopherol, Citric Acid, Alcohol Denat

    Key benefits

    ADDRESSES CELLULAR SENESCENCE

    Takes a senotherapeutic approach to cellular senescence, a hallmark of aging, to help support healthier cellular function and skin longevity.

    SUPPORTS SKIN STRUCTURE

    Supports healthy fibroblast function, promotes collagen synthesis, and the extracellular matrix—the structural network that contributes to skin firmness, strength, and resilience.

    Promotes Smoother, Firmer Skin

    Helps improve the appearance of fine lines, uneven texture, dullness, and loss of firmness for smoother, firmer, more even-looking skin.

    Supports Healthy Inflammatory Signaling

    Helps support a healthier cellular environment by addressing age-related inflammatory signaling associated with senescent cells, which can contribute to visible signs of aging.

    Improves Skin Resilience

    Supports skin's ability to recover and respond to cumulative environmental and age-related stress, helping maintain healthier skin function over time.

    How to use

    Shake well. Smooth 1-2 pumps onto face/neck/chest. If irritation occurs, discontinue use and consult physician. Keep in a cool, dry place out of direct light. Use within 6 months of opening.


    Who is it for?

    Designed for all skin types experiencing signs of biological or chronological aging, including:
    • Loss of resilience + slower to recover
    • Dullness, 
    • Fine lines
    • Uneven texture
    • Loss of firmness 
    • Cumulative environmental stress.


    Particularly suited to those seeking a targeted skin-longevity treatment or looking to expand an existing age-delay regimen.

    Serum vs Balm

    Senolytic Serum and Senolytic Balm are designed to complement one another. The lightweight Serum provides a more targeted approach to supporting cellular longevity, while the Balm builds on that approach with lipid nourishment, antioxidant protection, and barrier support.

    Senolytic Serum
    Senolytic Balm
    Primary Role
    Senolytic Serum Targeted cellular longevity support
    Senolytic Balm Cellular longevity + collagen and barrier support
    Key Actives
    Senolytic Serum Fisetin, Astragalus + Magnesium Ascorbyl Phosphate (MAP)
    Senolytic Balm Fisetin, Resveratrol, CoQ10 + Tetrahexyldecyl Ascorbate (THD)
    Texture
    Senolytic Serum Lightweight, layerable serum
    Senolytic Balm Rich, nourishing lipid-based balm
    Best For
    Senolytic Serum All skin types seeking targeted cellular longevity support
    Senolytic Balm Normal-to-dry, mature, sensitive, or depleted skin
    When to Use
    Senolytic Serum PM, after cleansing and toning
    Senolytic Balm PM, as the final step in your regimen

    Why use both?

    The formulas are designed to play different roles. Senolytic Serum provides targeted cellular longevity support, while Senolytic Balm broadens that approach with antioxidant protection, collagen support, and intensive barrier nourishment. Layer together for a more comprehensive approach to visible aging.