Radiant, youthful-looking skin starts with vitamin A and continues with vitamin C. Topically applied L-ascorbic acid, if stabilized and delivered properly, fights free radical damage, increases production of collagen, and reverses age-related changes in the interface between the dermis and the epidermis. There have been a number of recent technological advances that have allowed formulators like me to create natural, alternative products that noticeably reverse the effects of time. These breakthroughs include methods that permit the much more effective delivery of age-defying heavy hitters, including vitamin A (as retinol) and vitamin C (as L-ascorbic acid). Our winner in the skin rejuvenation department is Gentle Retinol Night Serum, our age-fighting topical that holds its own against its pharmaceutical counterpart and reigning champion, Retin-A. Cancer of the skin (including melanoma and basal and squamous cell skin cancers) is by far the most common of all types of cancer. According to one estimate, about 3.5 million basal and squamous cell skin cancers are diagnosed each year (occurring in about 2.2 million Americans, as some people have more than one). About eight out of 10 of these are basal cell cancers. Squamous cell cancers occur less often. However, according to the American Cancer Society, though melanoma is the least common of all diagnosed skin cancers at approximately 4%, it accounts for about 77% of cancer deaths. We’ve discussed how UVB rays could harm skin via direct DNA damage. The subsequent chromosomal alterations and mutations can initiate skin cancers, particularly the squamous or basal-cell types associated with UVB. Even if we use a non-nano zinc oxide sunscreen daily to block UV rays, sunscreen alone just does not provide complete protection. UV exposure is responsible for 90% of human nonmelanoma skin cancer. Of the UV light reaching the earth, 90% of the waves are UVA lengths (320-400 nm) and only 10% are the shorter UVB wavelengths (280-320 nm). Both UVA and UVB are studied for their skin cancer-causing potential, however focus has been on UVB. This is at least partially because UVB is considered a complete carcinogen—a substance able to initiate, promote and progress the development of skin cancer.